While the first one that came to mind for me was the intersection of I-25 and I-70 Denver which is called The Mousetrap. But my favorite actually comes from my cycling activities where a small rise on the outskirts of Boulder went right past a mini golf/go kart track and was affectionately known the Col d' Fun 'n Stuff.

Atlanta has Spaghetti Junction, the intersection of I-285 and I-85 and a couple of side street exits thrown in for good measure.
<img src="http://switchboard.nrdc.org/blogs/dlovaas/media/SpaghettiJunctionGA.jpg"width=500&gt;
In my neighborhood, there is also the Alpharetta Autobahn, GA 400. It gets that name for two reasons, the number of BMW, Mercedes, and Porsche on it and in off peak hours the average cruising speed is usually 80+ mph.

anyone who has driven on Indianapolis' I-465– speed limit 50-55– knows that it's "the bigger Speedway".. as most traffic drives 80+ (indianapolis + giant ring of pavement= high speeds)

Two separate three-lane interstates on Chicago's west side, I-88 and I-290, merge together to form a single, beautiful, harmonious piece of infrastructure called "The Hillside Strangler". There's also that bit of hell on the north side where the Edens and the Kennedy combine to become 20 lanes of pure, stagnant, glory.

The "Double Donuts of Doom" in Cambridge, MA. These two rotaries are about 300 feet apart. There's a traffic-light controlled crosswalk halfway between the rotaries. What could possibly go wrong?
Route 2 is Massachusetts' older east-west cross-state highway. Two lanes per side for most of the state, it's four lanes per side headed down into Cambridge, northwest of this section of map. US Route 3 is a north-south, passing through from NH on down to Boston's Southeast Expressway, but in around Boston it's a minor road. State Route 16 is a heavily travelled east-west city main street. They all come together for this part of the trip.
This road totally locks up for two hours in the morning rush time, and two hours in the evening rush time. That is, if there aren't any accidents, snow, ice, or other stupidity (like a pair of red-tailed hawks that set up a nest on a building about 500 feet north of the left-hand rotary; bird watchers slowed traffic down for weeks when the chicks were hatching).
<img src="http://tinyurl.com/5vtup2k&quot; />

We have the Mercer Mess, and the S-curves, but my favorite nicknamed stretches of roadway in the Seattle area are simply the floating bridges. There are less than 20 permanent floating bridges in the world and we have three spans. They float on the water (unless parts of them sink, which is uncommon but has happened). The image below is of the smallest span (520) and is typical of fall storms. The south side gets a lot of waves while the north side is flat calm. I used to commute over it but not any more.
<img src="http://www.allamericanpatriots.com/files/images/2008-04-wind-sr-520-floating-bridge.jpg"&gt;

There's a strech of I-84 in Oregon known to truckers as Cabbage Patch. It's scary as heck the first time you drive it, but fun.
It's about a dozen switchbacks. It'd be fun with something with less momentum than a 40=-ton semi!

I295N Delaware into Pa = "the Delaware Autobahn"
I95S into 495 = DC/NoVa mixing bowl

Didn't strike me until now, but Hamilton has The Linc, an east-west expressway across the whole city. Named for Lincoln Alexander, a local semi-famous dude.
We also have The Jolley Cut, which, while being fun to drive, is named after long-dead businessman James Jolley.

Big Beaver is actually sort of an "Official" nickname, it's really 15 mile Rd. 8 Mile is known as Baseline Drive.

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